| J. Neufeldt C., Cerikan B., Cortese M., Frankish J., Lee J., Plociennikowska A., Heigwer F. et al. |
SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB |
BioRxiv |
2020 |
preprint |
| Heigwer F., Boutros M. |
Cloud-Based Design of Short Guide RNA sgRNA Libraries for CRISPR Experiments |
Methods in molecular Biology |
2020 |
research article |
| Port F., Strein C., Stricker M., Rauscher B., Heigwer F. et al. |
A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila |
eLife |
2020 |
research article |
| Rauscher B., Henkel L., Heigwer F., Boutros M. |
Lineage specific core-regulatory circuits determine gene essentiality in cancer cells |
BioRxiv |
2019 |
preprint |
| Heigwer F., Scheeder C. et al. |
Time-resolved mapping of genetic interactions to model rewiring of signaling pathways |
eLife |
2018 |
research article |
| Scheeder C., Heigwer F., Boutros M. |
Machine learning and image-based profiling in drug discover |
Curr. Opinions in Systems Biology |
2018 |
Review |
| Heigwer F., Port F., Boutros M. |
RNA Interference Screening in Drosophila |
Genetics |
2018 |
Review |
| Rauscher B., Heigwer F., Henkel L. et al. |
Toward an integrated map of genetic interactions in cancer cells |
Molecular systems biology |
2018 |
research article Cover |
| Caicedo J. C., Cooper S., Heigwer F. et al. |
Data-analysis strategies for image-based cell profiling |
Nature Methods |
2017 |
Review, Cover |
| Scheeder C.*, Heigwer F. * & Boutros M. |
HTSvis: a web app for exploratory data analysis and visualization of arrayed high-throughput screens |
Bioinformatics |
2017 |
research article |
| Rauscher B.*, Heigwer F. * et al. |
GenomeCRISPR - a database for high-throughput CRISPR/Cas9 screens |
Nucleic Acids Research |
2017 |
research article |
| Heigwer F., Zhan T. et al. |
CRISPR library designer CLD: software for multispecies design of single guide RNA libraries |
Genome Biology |
2016 |
research article |
| Boutros M., Heigwer F., Laufer C. |
Microscopy-Based High-Content Screening |
Cell |
2015 |
review |
| Winter J., Breinig M., Heigwer F. et al. |
caRpools: An R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens |
Bioinformatics |
2015 |
research article |
| Volz H. C.*, Heigwer F. * et al. |
Single-cell phenotyping of human induced pluripotent stem cells by high-throughput imaging |
bioRxiv |
2015 |
preprint |
| Heigwer, F. et al. |
E-CRISP: Fast CRISPR target site identification |
Nature Methods |
2014 |
research article |
| Heigwer, F. et al. |
E-TALEN: a web tool to design TALENs for genome engineering |
Nucleic acids research |
2013 |
research article |
| Kitanovic, A. *, Bonowski, F. *, Heigwer, F. * et al. |
Acetic acid treatment in S. cerevisiae creates significant energy deficiency and nutrient starvation that is dependent on the activity of the mitochondrial transcriptional complex Hap2-3-4-5 |
Front. Oncol. |
2012 |
research article |
| Holenya, P. *, Heigwer, F. * and Wölfl, S. |
KOMA: ELISA-microarray calibration and data analysis based on kinetic signal amplification |
Journal of Immunological Methods |
2012 |
research article |
| Holenya, P. *, Kitanovic, I. *, Heigwer, F. and Wölfl, S. |
Microarray-based kinetic colorimetric detection for quantitative multiplex protein phosphorylation analysis |
Proteomics |
2011 |
research article |
